Sadie Marjani

Representative publications:

Mai L, Wen Z, Zhang Y, Gao Y, Lin G, Lian Z, Yang X, Zhou J, Lin X, Luo C, Peng W, Chen C, Peng J, Liu D, Marjani SL, Tao Q, Cui Y, Zhang J, Wu X, Weissman SM, Pan X. Shortcut barcoding and early pooling for scalable multiplex single-cell reduced-representation CpG methylation sequencing at single nucleotide resolution. Nucleic Acids Res. (2023) Nov 27;51(21):e108. doi: 10.1093/nar/gkad892. 

Linkai Zhu, Sadie L. Marjani*, Zongliang Jiang*. The Epigenetics of Gametes and Early Embryos and Potential Long-Range Consequences in Livestock Species-Filling in the Picture With Epigenomic Analyses. Frontiers in Genetics. (2021) Mar 3;12:557934. doi: 10.3389/fgene.2021.557934. *denotes corresponding author.

Wang H, Gong P, Chen T, Gao S, Wu Z, Wang X, Li J, Sadie L. Marjani, Costa J, Weissman SM, Qi F, Pan X, Liu L. Colorectal Cancer Stem Cell States Uncovered by Simultaneous Single-Cell Analysis of Transcriptome and Telomeres. Advanced Science (Weinh). (2021) Feb 8;8(8):2004320. doi: 10.1002/advs.202004320. 

Liyou An, Sadie L. Marjani, Zhisong Wang, Zhihui Liu, Ruihai Liu, Fei Xue, Jie Xu, Tshimangadzo L. Nedambale, Lan Yang, X. Cindy Tian, Lei Su and Fuliang Du. Magnesium is a critical element for competent development of bovine embryos. (2019) Theriogenology. Vol. 140:109–116. doi:10.1016/j.theriogenology.2019.08.015.

Jingyue Ellie Duan, Zongliang Jiang, Fahad Alqahtani, Ion Mandoiu, Hong Dong, Xinbao Zheng, Sadie L. Marjani, Jingbo Chen and Xiuchun Cindy Tian. Methylome Dynamics of Bovine Gametes and in vivo Early Embryos. (2019) Frontiers in Genetics. Vol. 10:512 doi:10.3389/fgene.2019.00512. 

Zongliang Jiang, Jianan Lin, Hong Dong, Xinbao Zheng, Sadie L. Marjani, Jingyue Duan, Zhengqing Ouyang, Jingbo Chen and Xiuchun (Cindy) Tian. DNA methylomes of bovine gametes and in vivo produced preimplantation embryos. (2018) Biology of Reproduction. 1;99(5):949-959. doi: 10.1093/biolre/ioy138.

Jialing Zhang*, Stephan Stanislaw Späth*, Sadie L. Marjani, Wengeng Zhang and Xinghua Pan. Characterization of cancer genomic heterogeneity by next-generation sequencing advances precision medicine in cancer treatment. (2018) Precision Clinical Medicine. 1(1) 29–48, doi: https://doi.org/10.1093/pcmedi/pby007. *denotes co-first authors.

Lin Han*, Hua-Jun Wu*, Haiying Zhu, Kun-Yong Kim, Sadie L. Marjani, Markus Riester, Ghia Euskirchen, Xiaoyaun Zi, Jennifer Yang, Jasper Han, Michael Snyder, In-Hyun Park, Rafeal Irizarry, Sherman M. Weissman, Franziska Michor, Rong Fan and Xinghua Pan. Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells. (2017) Nucleic Acids Res. doi: 10.1093/nar/gkx026. *denotes co-first authors.

Wanjun Zhu*, Xiaoyan Zhang*, Sadie L. Marjani, Shixiu Wu, Xinghua Pan. Next-Generation Molecular Diagnosis: Single-Cell Sequencing from Bench to Bedside. (2016) Cellular and Molecular Life Sciences. doi:10.1007/s00018-016-2368-x. *denotes co-first authors.

Zongliang Jiang, Patrick Harrington, Ming Zhang, Sadie L. Marjani, Joonghoon Park, Lynn Kuo, Csaba Pribenszky and Xiuchun Cindy Tian. Effects of High Hydrostatic Pressure on Expression Profiles of In Vitro Produced Vitrified Bovine Blastocysts. (2016) Scientific Reports. 6:21215.

Xiaoyan Zhang, Sadie L. Marjani, Zhaoyang Hu, Sherman Weissman, Xinghua Pan, Shixiu Wu. Single-Cell Sequencing for Precise Cancer Research: Progress and Prospects. (2016) Cancer Research. 76(6):1305-12.

Zongliang Jiang, Hong Dong, Xinbao Zheng, Sadie L. Marjani, David M. Donovan, Jingbo Chen, Xiuchun Cindy Tian. mRNA Levels of Imprinted Genes in Bovine In Vivo Oocytes, Embryos and Cross Species Comparisons with Humans, Mice and Pigs. (2015) Scientific Reports. 5:17898.

Cindy Tian and Sadie L. Marjani. “Epigenetics of Cloned Preimplantation Embryos of Domestic Animals.” Livestock Epigenetics. West Sussex, UK: WILEY-BLACKWELL, 2012.

Sadie. L. Marjani, Daniel Le Bourhis, Xavier Vignon, Yvan Heyman, Robin E. Everts, Sandra L. Rodriguez-Zas, Harris A. Lewin, Jean-Paul Renard, Xiangzhong Yang and X. Cindy Tian. Embryonic gene expression profiling using microarray analysis. (2009) Reproduction, Fertility and Development. 21(1): 22-30.

Sadie. L. Smith, L-Y. Sung, R.E. Everts, R. Page, B. Henderson, F. Du, T.L. Nedambale, S. Rodriguez-Zas, J-P. Renard, H.A. Lewin, X. Yang & X. C. Tian. Global Gene Expression Profiling of Single Bovine Embryos Uncovers Significant Effects of In Vitro Maturation, Fertilization and Culture. (2009) Molecular Reproduction and Development. 76(1):38-47.

Xiangzhong Yang, Sadie L. Smith, X. Cindy Tian, Harris A. Lewin, Jean-Paul Renard, Teruhiko Wakayama. Nuclear reprogramming in cloned embryos and its implications for therapeutic cloning. (2007) Nature Genetics 39:295-302.

Sadie. L. Smith, R. E. Everts, X. C. Tian, F. Du, L-Y. Sung, S. Rodriguez-Zas, B-S. Jeong, J-P. Renard, H. A. Lewin, & X. Yang. Global Gene Expression Profiles Reveal Significant Nuclear Reprogramming by the Blastocyst Stage after Cloning. (2005) Proc. Natl. Acad. Sci. USA 102:17582-17587.